What sets Reishi mushrooms apart from pharmaceuticals and what makes it particularly effective is the synergistic effect of the combined bio-active compounds, such as the beta-glucans, glycoproteins/proteo-glycans, polyphenols and triterpenes.
Oriveda's Reishi Primo is a dual extracted and highly concentrated red Reishi fruiting body extract. It has been optimised for the compounds that make Reishi worth considering: triterpenes, polyphenols and beta-glucans.
Oriveda's Reishi Primo has one of the highest bio-active compounds available globally.
Oriveda Reishi Primo ®
120 vegetable capsules @ 300 mg
2 months supply (recommended dose: 2 capsules per day)
> 9.4 % triterpenes
> 16 % beta-glucan
> 1.8 % polyphenols
- Dual extracted
- 100% Red Reishi fruiting bodies
- Extracted using hot water and alcohol
- Cultivated on wood logs ('duanwood')
- No fillers, flow agents or additives, GMOfree, nonirradiated
Click here to see our authorised 'Supplement Facts' & Click here to see the most recent third party test results.
Produced in compliance with the following quality standards :
ISO 9001:2008, ISO 22000:2005, HACCP, cGMP
Halal, Koosjer, USDA organic (EcoCert)
What sets Reishi mushrooms apart from pharmaceuticals and what makes them particularly effective is the synergistic effect of the combined bio-active compounds (mainly Beta-Glucans, glycoproteins/proteo-glycans, polyphenols and triterpenes). Extraction defines the therapeutic potency, since we cannot digest non-extracted mushrooms properly. (Read an article about extraction process and why it matters by clicking here). Extraction is essential for an actual therapeutic effect and dual extraction enable both water-solubles and insolubles to become bio-available (meaning your body can absorb it!). The immunological effects of mushroom extracts many, many times higher when compared against non-extracted powders.
Hot water extracts (incl. home made Reishi tea), tinctures and powdered products contain low concentrations of bioactives (which is why you never see them specified on the label of such products - it's better to keep it vague from a vendor's perspective). The bioavailability is always a major problem - if we can't digest all that good stuff we can't benefit from it, right?
Reishi Primo is one of the very few Reishi products that actually offers all those bioactives in a bioavailable form, guaranteeing not only the presence but also the quantity of those compounds. Odd as it may seem, it is actually rare to find Reishi with clear specifications, let alone verifiable specifications. ORIvEDA's mantra is and always will be: quality claims should be supported by third party test reports to be reliable and trustworthy.
Reishi Primo is produced using a multi-step extraction procedure (hot water, alcohol, alcohol precipitation) which ensures a high purity product, as opposed to extraction using only hot water or a mix of water and alcohol in a single-step extraction process.
For your interest, see how Oriveda did its due diligence when developing Reishi Primo by reading this article, with a lot of objective background information about cultivation, extraction and other Reishi supplements.
A 2017 report concluded almost all Reishi sold in the US is not actually Reishi(!!) and many that do, lack quality - it's worthwhile reading material for your quest to find the best Reishi product.
Reishi is no doubt the most famous of all medicinal mushrooms and it is one of very few with such a long history of use; some -though unverifiable- sources state it was probably already used 5000 years ago. ‘Reishi’, the name most people are familiar with, is in fact a Japanese interpretation of the oldest Chinese name; Ruizhi (meaning ‘auspicious mushroom’). The most common name used in China is ‘Ling Zhi‘
Research suggests that Reishi’s bioactive constituents (Polysaccharides, Triterpenes, Nucleosides, minerals and trace elements) are in particularly therapeutically effective when they can benefit from each other’s presence; the so-called synergistic effect.
A full-spectrum product will contain all bio-actives, but in order to benefit from their therapeutic potential this full-spectrum product should be an extract. The majority of the bio-actives are embedded in the indigestible chitin cell-walls of the mushroom, not in the cell itself, like with most herbs. Extraction is essential to break the cell-walls and set the bio-actives free from their chitin chains.
Many people are under the impression that because wild Reishi is rare and very expensive it must be of better quality than the cultivated version, therapeutically speaking. The opposite is true, however. Wild Reishi is easily damaged and contaminated by insects, moulds, environmental pollution and the overall amount of bioactives is very inconsistent, resulting in an unreliable quality. It rarely reaches full maturity in perfect condition. Cultivated Reishi on the other hand is usually based on strains selected for their therapeutic potency and it can be grown under well controlled circumstances. This results in a more uniform and reliable product.
Among the wide range of diseases claimed to be successfully ‘treated*‘ by Reishi are found to be:
*in addition to cancer, bronchitis and hypertension.
Some people taking a high serving of 1.5 - 9 grams (our recommendation is 600milligrams) per day reported one or more of the following side effects: temporary sleepiness, thirst, rashes, bloating, frequent urination and diarrhoea. Taking the extract together with vitamin C seemed to improve many of the side effects. Lowering the serving size also helped.
These reports do not give details about the quality and properties of the extracts that were consumed; and taking into account the poor quality level of most Reishi products (see this 2017 report) it is not unlikely that at least some of these side effects might be related to that, so this appears not to be a direct cause for alarm.
Possibly neutralising antibiotics
As said, the anti-microbial combination of Reishi with four commonly used antibiotics resulted in an additive or synergistic effect in most, but not all, instances. Reishi appears to cause cefazolin and ampicillin to be less effective against Proteus vulgaris (known to cause urinary tract infections and wound infections).
However, it is also known that consuming milk with antibiotics can neutralise the effect of the medicine (source).
Avoid when using immune suppressants
Reishi extracts rich in triterpenes are very powerful; these might not be the best choice for everybody.
Reishi with a high level of triterpenes should not be used in hormone-related breast cancers - there are contradicting results, so it is best to stay on the safe side. The anti-androgenic effects of Reishi can suppress libido.
Because Reishi has immune-balancing properties, it should not be used together with immune-suppressants, like those prescribed after a transplant. The blood sugar lowering effects can cause fatigue in those that are highly susceptible. In general these people are also very susceptible to e.g. caffeine and alcohol, or are diabetic. Taking the extract together with a sugar-containing liquid can neutralise this effect.
Rare side effects are:
not sleeping well, bad/vivid dreams, feelings of anxiety, feeling mentally numb/clouded or having a sense of heightened mental activity. These effects are most likely caused by a genetic anomaly, like overreacting to specific triterpenes, such as lanostan. Just like with Cordyceps some people experience effects that are exactly the opposite of what usually happens. This is personal and due to genetic wiring.
Lanostan triggers the function of the adrenal glands, which are responsible for adrenaline/nor-adrenaline production. If you’re very sensitive to this you can experience hyper-activity which can make you feel anxious, etc. If you experience daily stress on top of that, this will also push the production of adrenaline/noradrenaline in your body, potentially causing anxiety.
Reishi Primo contains a relatively high level of triterpenes; if you experience these side effects it might be better to look for a different mushroom extract or to choose a hot-water-extracted-only Reishi extract, which contains no triterpenes.