Maitake

120 vegetable-capsules @ 400 mg
2 month supply (recommended dose: 2 capsules per day)

Detailed leaflet included with every order

Bioactive compounds:
> 38 % beta-glucan
> 1.20 % polyphenols

- hot water extract -

Please click here to see our authorised 'Supplement Facts' label.

Third party certified test for purity and potency here.

Produced in compliance with the following quality standards :
ISO 9001:2008, ISO 22000:2005, HACCP, cGMP
&
Halal, Koosjer, USDA organic (EcoCert)

In Japanese, ‘Mai’ means dance and ‘Take’ means mushroom, thus ‘Dancing Mushroom’. Until about 1980 Maitake was only available from the wild.Approximately 2000 years ago, Maitake was used in Traditional Chinese Medicine for improving the health of the spleen and stomach, calming nerves and treating haemorrhoids.

In more recent animal experiments and human clinical trials, Maitake was found to have promising anti-tumor and anti-viral properties. Other therapeutic uses of this mushroom include blood pressure regulation, control of diabetes, normalising cholesterol levels, treatment of chronic fatigue syndrome (CFS), and anti-HIV activity.

Please click here to see our authorised 'Supplement Facts' label. And then use Google to look for additional details on Maitake's therapeutic potential - you will read about the 'D-Fraction®*', the 'MD-Fraction' and others.

The d-fraction is originally a term coined in the 1980s; it referred then to a purified -fractionated- beta-glucan, bonded with a protein; a so-called 'proteoglycan'. This particular fraction showed a lot of promise because of its anti-tumor potential.

Unfortunately, neither this product nor its successor, the md-fraction (a more pure version of the d-fraction, patented in 1997) is for sale in its undiluted pure form; the production costs are probably too high (it's a 200 : 1 extract) and the fractionating process is too complex for mass-production.

Although the manufacturers prefer to keep the details as vague as possible (marketing reasons), here are some -verifiable- facts:

• Apart from being a research-term, 'D-Fraction®' is a trademark*, registered in 1995. Products sold with the name 'D-Fraction®' contain, according to the label 'PD-Fraction®*' (which stands for 'Pre-D-Fraction'). It is unclear what this is.
• The commercial supplement 'D-Fraction®' has been tested against another Maitake supplement, MaitakeGold 404®* (MTG), containing diluted version of the md-fraction. The test involved many immunological parameters. MTG scored significantly better in all tests.
• MTG is standardised for ≥ 20% beta-glucans (though not on the label). Nothing else.
  The glucan/protein ratio is not revealed, although this would be an easy and cheap way to authenticate the product as being pure (the ratio should be between ± 2 : 1 (= d-fraction purity) all the way to 99 : 1 (= md-fraction purity) according to the patents).
• MTG is sold only in liquid form; 1 gram of extract dissolved in 30 ml of liquid. The recommended daily dosage is 8 - 16 drops daily, which equals 19 - 77 mg MTG.The optimal dosage of this extract is, according to independent research is 7 mg/kg bodyweight/day (e.g. a 60 kg person should take ± 420mg daily), which is significantly more.
• ORIVeDA's Grifolan® is standardised for ≥ 35 % beta-glucans, has a glucan/protein ratio of 2.5 : 1 (equals the original d-fraction) and can deliver the recommended daily dosage for optimal immunological effect easily. Because the extract used in the research was more pure than any commercially available product, the dosage should be adjusted accordingly: we recommend at least 4 - 8 capsules per day (each with ≥ 150 mg beta-glucans) if maximum therapeutic potential is needed. (The standard dose for normal immune support is 2 capsules daily.)

Summarising: Based on the existing facts we feel confident ORIVeDA Grifolan® is at least equal to, if not more potent than the best of the current commercially available Maitake products. Apart from that, the value for money is much better.

*D-Fraction® and PD-Fraction® are trademarks of Mushroom Wisdom, Inc., NJ, USA. MaitakeGold 404® (MTG) is a trademark of The Tradeworks Group, VT, USA

1. Normalising the immune function:

Maitake is known in SE-Asia as the King of Immunity. The purified beta-glucan/proteoglycan high molecular weight fractions in particular have promising anti-cancer and anti-viral properties, achieved by stimulating the production of cytokines, macrophages, NK-cells and cytotoxic T-cells. It stimulates the production of IL-1, IL-2 and others.

2. Anticancer adjuvant:

In combination with regular therapy (chemo, radiation) Maitake can lessen the side effects of these treatments and improves the quality of life.

3. Anti-HIV: The high molecular weight fractions show an enhancing effect on helper T-cells (CD4+), the target cells of HIV. Viral load decreased.

4. Positive effect on Chronic Fatigue Syndrome(CFS)

5. Positive effect on persistent vaginal Candida albicans proliferation and uterine fibroids

6. Helps with diabetes: Increases insulin sensitivity and lowers blood sugar (in particular Maitake fractions with a lower molecular weight)

7. Lowers blood pressure and helps to prevent an increase of blood pressure.

8. Helps to normalize the balance between good and bad cholesterol (HDL and LDL).

9. Also shows a liver-protecting effect.

For sensitive people the blood pressure lowering effect can occur as an unwanted side effect when taking therapeutic doses. Despite this, Maitake is considered very safe, even at doses of 1600 mg/kg/day no negative effects were found.